Correct placement and orientation of given sidechains and ligands, as well as correct placement of end-capsįor an example of what exactly they look for in the on-site model, see the 2010 National Tournament On-site Rubric and the 2011 National Tournament On-site Rubric.The model must be correctly folded, the end-caps placed at the correct ends of the protein chain, and the given sidechains or ligands attached to the Mini-Toober at the correct locations and with the correct orientations. At the competition, students will be given a Mini-Toober of the correct length, at the same scale of 2 cm per amino acid residue, foam representations of important sidechains or associated ligands, and red and blue plastic end-caps representing the carboxy and amino termini of the protein chain respectively. Relevance and creativity of "creative additions" (i.e., labeling the "fusion peptide" on hemagglutinin would get you points, but displaying every sidechain wouldn't, since that doesn't show any understanding of the protein's function)įor an example of how specific the pre-build model has to be (and of what constitutes good "creative additions"), see the 2010 National Tournament Pre-build Rubric and the 2011 National Tournament Pre-build Rubric.įor the on-site model, a file will be specified from the Protein Data Bank, but the specific section of this protein that students are to build will not be stated until the competition.Relevance and correct placement of sidechains or ligands you've chosen to display (and clarity/accuracy of the explanation on your card), as well as correct placement of end-caps.Accuracy of tertiary structure (3D arrangement of secondary structures- e.g., two strands of a beta sheet being correctly placed next to each other, and a nearby helix being perpendicular to both).Accuracy and correct placement of secondary structures (alpha helices and beta sheets).These additions must be explained on a two-sided, 3x5 index card, along with a paragraph explanation of how they are relevant to the protein's function, and submitted with the model, typically at impound. Students must decide for themselves which sidechains and/or ligands are important to the protein's function and should be displayed. The model must be correctly folded, and the end-caps placed at the correct ends of the protein chain, but the model must also include "creative additions" that showcase the function of the selected protein. Students will be provided beforehand with a Mini-Toober of the correct length, at a scale of 2 cm per amino acid residue, and red and blue plastic end-caps representing the carboxy and amino termini of the protein chain respectively. For the pre-build model, a section of a certain protein will be specified from the Protein Data Bank.
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